InVivo offers a recombinant form of Human Carcinoembryonic antigen-related cell
adhesion molecule 5 (CEACAM5 or CEA), which is produced under serum‐free conditions in
HEK 293 cells.
The expression construct contains residues 1 to 677 of human CEA and with a 25 amino acid
C-terminal truncation (Δ678–702) compared to full-length CEA, which contains 702 amino acids.
The amino acid sequence is identical to residues 1 to 677 of GenBank entry AAA62835.1. With
respect to reviewed UniProtKB entry P06731, this construct contains five sequence deviations:
N359I, N360I, Q361R, F641L, T646Q.
The recombinant protein is produced under serum‐free conditions in optimized HEK293-cell
system and purified through using ion exchange chromatography and Size Exclusion
Chromatography.
| Product-ID: |
RP_SZ_196 |
| Expression System: |
Mammalian; HEK |
| Protein Accession # : |
P06731 |
| Amino Acids: |
Met1–Ser677 |
| Mutations: |
N359I, N360I, Q361R, F641L, T646Q |
| Mature Protein N-Term: |
Lys35 (predicted) |
| Tag: |
none |
| Expected Molecular Weight: |
70.7 kDa (glycosylated form runs at 85-200 kDa on SDS-PAGE) |
| Formulation: |
Liquid, PBS, pH 7.4 |
| Concentration: |
≥ 0.5 mg/mL (photometric) |
| Activity: |
CEA Kryptor assay |
| Purity: |
≥ 90 % (Analytical SEC) |
The product is for research use or for further manufacturing only.
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