HLA-DR mAb (L243), InVivoPure

ID: AK3605P Category:

HLA-DR mAb (L243) is recommended for detection of a nonpolymorphic HLA-DR epitope 1-3 of human origin by IF, IHC(P) and FCM; non-cross-reactive with HLA-DQ or HLA-DP molecules.

This antibody is produced exclusively under serum-free conditions from hybridoma and purified with Protein-A or Protein-G affinity chromatography.

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Delivery time: 2-5 days

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Endotoxin level ≤ 2 EU/mg

HLA-DR mAb (L243) is recommended for detection of a nonpolymorphic HLA-DR epitope 1-3 of
human origin by IF, IHC(P) and FCM; non-cross-reactive with HLA-DQ or HLA-DP molecules. The
HLA-DR antigen is expressed on B lymphocytes, activated T lymphocytes and NK cells,
monocytes, macrophages, dendritic cells other antigen-presenting cells and progenitor cells.

This antibody is produced exclusively under serum-free conditions from hybridoma and
purified with Protein-A or Protein-G affinity chromatography.

 

Product-ID: AK3605P
Clone: L243
Immunogen: Animals were immunized with RPMI 8866 cells. Spleen cells were fused with NS-1 myeloma cells
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2a κ
Formulation: Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered
Concentration: ≥ 1.00 mg/mL
Purity: ≥ 90 % (CGE, reducing conditions)
≤ 10 % aggregates (analytical SEC)
Endotoxin: ≤ 2 EU/mg (LAL test)
Storage: 2 - 8 °C
Recommended Isotype Control: Mouse IgG2a ĸ Isotype Control (AK3399P)

 

The product is for research use only and not for use in diagnostic or therapeutic procedures.

The HLA-DR monoclonal antibody (clone L243) was purified from supernatant of HB-55™ L243 from the ATCC. The ATCC trademark and trade name and any and all ATCC catalog numbers are trademarks of the American Type Culture Collection.

Additional information

Literature

[1] Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Hurley CK, Mach
B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI,
Trowsdale J. Nomenclature for Factors of the HLA System, 2004. Hum Immunol. 2005 May;66(5):571-636. doi:
10.1016/j.humimm.2005.02.002. Epub 2005 Mar 3. PMID: 15935895.

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Product Information Sheet – AK3605P

Notice

The product is for research use only and not for use in diagnostic or therapeutic procedures.

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