CD8α mAb (2.43), InVivoPure
The CD8α mAb (2.43) reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha.
This antibody is produced exclusively under serum-free conditions from hybridoma and purified with Protein-A or Protein-G affinity chromatography.
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Endotoxin level ≤ 2 EU/mg
The CD8α mAb (2.43) reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or
CD8 alpha. The CD8α mAb (2.43) is widely used as a phenotypic marker for mouse CD8 on
cytotoxic T cells, thymocytes, as well as on certain cell types that do not also express the TCR,
including some NK cells and lymphoid dendritic cells.
This antibody is produced exclusively under serum-free conditions from hybridoma and
purified with Protein-A or Protein-G affinity chromatography.
| Product-ID: | AK3604P |
|---|---|
| Clone: | 2.43 |
| Immunogen: | Animals were immunized with CTL Clone L3 cells. |
| Host: | Rat |
| Clonality: | Monoclonal |
| Isotype: | IgG2b κ |
| Formulation: | Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered |
| Concentration: | ≥ 1.00 mg/mL |
| Purity: | ≥ 90 % (CGE, reducing conditions) |
| ≤ 10 % aggregates (analytical SEC) | |
| Endotoxin: | ≤ 2 EU/mg (LAL test) |
| Storage: | 2 - 8 °C |
The product is for research use only and not for use in diagnostic or therapeutic procedures.
The CD8α monoclonal antibody (clone 2.43) was purified from supernatant of TIB-210™ 2.43 from the ATCC. The ATCC trademark and trade name and any and all ATCC catalog numbers are trademarks of the American Type Culture Collection.
Additional information
| Literature | [1] Zamoyska R. The CD8 coreceptor revisited: one chain good, two chains better. Immunity. 1994 Jul;1(4):243-6. |
|---|---|
| Document | |
| Notice | The product is for research use only and not for use in diagnostic or therapeutic procedures. |
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